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Metabolic Accelerator PM is a stimulant-free fat burner that increases your metabolic rate and activates brown fat cells, making it a great supplement to take if your goal is to lose weight.
Each serving of Metabolic Accelerator PM contains a clinical dosage of CaloriBurn GP™. Scientific literature has dubbed CaloriBurn PM as the “Holy Grail” of optimizing body composition and fat loss.
This formula wouldn’t be complete without a blend of natural herbs that will help calm your body and mind to help you get a restful sleep.
Getting rid of stubborn body fat is tough and it gets tougher as we age. Sometimes dieting, exercising and getting a good nights rest just isn’t enough to lose that stubborn fat that you’ve been carrying around for years. This is where the addition of a powerful, stimulant-free metabolic accelerator can make a HUGE difference.
There are three key reasons, which hold many people back from burning more body fat:
- Our metabolism slows at night
- We don’t sleep well
- Your “Fat Burner” Contains Ineffective Ingredients
With Metabolic Accelerator PM you can successfully address these. First, Metabolic Accelerator PM helps increase calorie burning while you sleep. By supporting your resting metabolic rate, it helps create an environment that is more conducive to overnight fat-burning.
Next, Metabolic Accelerator PM promotes deeper sleep. Chances of you walking around the house at night with food and hunger cravings are diminished.
Furthermore, sleeping well helps keep cortisol levels lower. Cortisol is a stress hormone, that gets in the way of losing weight.
CaloriBurn GP™ - The “Holy Grail” of fat loss Ingredients
CaloriBurn™ is an ultra-pure, high-quality Grains of Paradise extract and is considered by researchers to be the “Holy Grail” when it comes to fat loss. Though there are many decent grains of paradise extracts out there, Ketond took things up a notch including it into our Metabolic Accelerator PM.
CaloriBurn™️ is derived using complex techniques in-line with both high performance liquid chromatography (HPLC) and high performance thin-layer chromatography (HPTLC).
While both practices are among the best chemical validation techniques in science, HPLTC is regarded as one of the most powerful and efficient analytical tools for inferring overall makeup and purity of pharmaceutical drugs.
Metabolic Accelerator PM – A Powerhouse Stimulant-Free Thermogenic
CaloriBurn™ Grains of Paradise (GP), also known as Aframomum melegueta, is a member of the Ginger family, a family of roots that has been used to treat various ailments and illnesses in Traditional Chinese Medicine (TCM) and Ayurvedic medicine for ages. Though this family of herbs grows plentiful in much of Asia, GP is most abundant in West Africa, where the seeds of the plant have long been utilized as a spice in cooking.
With such high concentrations of strong bioactive compounds like 6-gingerol, 6-paradol, and 6-shogaol, grains of paradise seeds pack quite a bit of heat when used to flavor recipes! However, as modern science continued to investigate the biological properties, they slowly discovered more and more about the plant, unveiling other potential uses.
Research has shown that the individual components that make up GP seeds have some strong capabilities, with gingerol typically grabbing most of the spotlight. This chemical has proved impressive in terms of its abilities to lower blood glucose and reduce inflammation,[4,5] which has made ginger and its relative favorites within the health world. Other research has found similar capabilities in both paradol and shogaol, with the former of which also showing promise as a neuroprotective substance. But all three together, such as is the case in GP, and you really start cooking.
Decreased Blood Glucose Levels
In 2013, researchers found that varying doses of Aframomum melegueta decreased blood glucose in a dose-dependent manner, an effect that coincides with what we’d expect – the individual components have shown potential in blood sugar management, so it makes sense the entire extract does, too. If you know anything about blood glucose level management, you know how crucial it is in regulating body weight, specifically in body fat storage.
If you’re constantly burning sugar and have elevated blood sugar and insulin levels, you won’t be beta-oxidizing (ie burning) fat![9,10] And, as it turns out, that’s not all GP does in terms of fat mass!
The key – targeting brown adipose tissue!
Researchers found that the GP group experienced decreased visceral fat in the lower abdomen while the placebo group saw slightly increased visceral fat in the same area.
Most know that when the body is in a caloric surplus (eg. the body has more energy available than it needs) and insulin levels are high, it stores that energy for later use. Once muscles are adequately fed and supported, the body’s preferred storage method is to turn that excess energy into adipose tissue, or fat. There are two kinds of fat, white adipose tissue and brown adipose tissue. White adipose tissue is, at its core, a storage site – it’s main function is to hold energy. However, brown adipose tissue is a bit more of the “expendable” kind, dissipating its caloric value in order to generate heat.
While we don’t have much control over the split between white fatty tissue and brown fatty tissue, it’s highly desirable to have more brown fatty tissue compared to the “hard-to-lose” white fatty tissue. Research has found that holding a higher ratio of brown fatty tissue can potentially increase energy expenditure, and in turn, decrease body fat. In simple terms, brown fat is more willing to give itself up for use, leading it paramount importance in a weight-loss endeavor.
By expending energy previously stored as brown adipose tissue, it’s possible to not only maintain energy levels but also lose body fat. For anyone interested in losing weight, this is an obvious desire, so we need to flip this metabolic switch. It turns out this process may be aided by supplementing with grains of paradise!
Bringing the heat in clinical research…
In 2011, researchers injected lab mice with GP extract in order to measure the relationship between the spice and brown fatty tissue. What they found confirmed a positive relationship – not only did GP stimulate nerve activity within brown fatty tissue, the effects lasted for as long as three hours! Furthermore, they found that the temperature of the tissue increased in response to this stimulation.
By activating brown fatty tissue and raising body temperature, the body responds pretty simply – burn it off and maintain normal temperatures. The outcome? More energy expenditure, less body fat, and a return to baseline normalcy!
Great preliminary research, but that was an injection into animals — clearly we needed more data:
Acute usage works…
Energy expenditure change (ΔEE) after oral ingestion of Grains of Paradise. This spice helps melt away those stubborn pounds!
Evidence of the above relationship encouraged further investigation, and researchers undertook the challenge in 2013. Using an ethanol-derived extract of grains of paradise, 19 healthy men between the ages of 20 and 23 were administered 40mg of GP in a single-blind, placebo-controlled study. After 24 hours, scientists measured whole body energy expenditure and compared it to rates prior to taking the extract.
They found that although no differences existed between groups before administration, those that took grains of paradise raised energy expenditure levels by 5% in only two hours compared to the control group. Grains of paradise, in a way, targeted brown adipose tissue for use and was effectively able to burn it off!
5% may not seem like a lot, and it certainly doesn’t mean we can stuff our faces full of donuts fried in vegetable oil, but any dieter who’s hit a plateau would gladly take that 5% increase – especially if it can be taken twice a day for a month!
…and usage from daily use works too!
The researchers in the previous study took things a step further – in 2014, they decided to expand their timespan to a full month, while setting GP dosage to 30mg per day. In this single-blind, placebo-controlled study, 19 healthy females aged between 20 and 22 either took 30mg of GP per day or a placebo, with whole-body energy expenditure and visceral body fat tested at the beginning and end of the study.
Upon completion, the spice proved successful yet again – those given grains of paradise significantly increased energy expenditure and decreased visceral (organ-surrounding) fat. These results were statistically significant both for each subject and across groups, as well, with the GP group burning around 100 calories more per day than placebo!
However, it’s important to note that the researchers did not see any significant changes in subcutaneous (under-the-skin) fat or in overall body fat. This led the researchers to conclude that GP can help attenuate weight gain, though mainly in “preventing visceral fat accumulation.”
In other words, Metabolic Accelerator PM can certainly give you a fat-burning boost, but it will by no means do all the work for you!
1 Attimarad, Mahesh et al; “High-performance thin layer chromatography: A powerful analytical technique in pharmaceutical drug discovery.”; Pharmaceutical methods; vol. 2,2; 2011; 71-5; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658041/
2 Sugita, Jun, et al; “Grains of Paradise (Aframomum Melegueta) Extract Activates Brown Adipose Tissue and Increases Whole-Body Energy Expenditure in Men.”; The British Journal of Nutrition; U.S. National Library of Medicine; Aug. 2013; https://pubmed.ncbi.nlm.nih.gov/23308394
3 Tackie AN, Dwuma-Badu D, Ayim JSK, Dabra TT, Knapp JE, Slatkin DJ, Schiff PL., Jr. “Constituents of West African medicinal plants. VIII. Hydroxyphenylalkanones from Amomum melegueta” Phytochemistry. 1975;14:853–854; https://agris.fao.org/agris-search/search.do?recordID=US201302734991
4 Al-Amin, Zainab M, et al; “Anti-Diabetic and Hypolipidaemic Properties of Ginger (Zingiber Officinale) in Streptozotocin-Induced Diabetic Rats.”; The British Journal of Nutrition; U.S. National Library of Medicine; Oct. 2006; https://pubmed.ncbi.nlm.nih.gov/17010224/
5 Jolad, Shivanand D, et al; “Commercially Processed Dry Ginger (Zingiber Officinale): Composition and Effects on LPS-Stimulated PGE2 Production.”; Phytochemistry; U.S. National Library of Medicine; July 2005; https://pubmed.ncbi.nlm.nih.gov/15996695
6 Wei, Chien-Kei et al; “6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice.”; International journal of molecular sciences; vol. 18,1; 168; 17 Jan. 2017; doi:10.3390/ijms18010168; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297801/
7 Gaire, Bhakta Prasad et al; “Neuroprotective effect of 6-paradol in focal cerebral ischemia involves the attenuation of neuroinflammatory responses in activated microglia.”; PloS one; vol. 10,3; e0120203; 19 Mar. 2015; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366308/
8 Ilic, Nebojsa et al.; “Toxicological evaluation of grains of paradise (Aframomum melegueta) [Roscoe] K. Schum.”; Journal of ethnopharmacology; vol. 127,2; 2010; 352-6; doi:10.1016/j.jep.2009.10.03; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815460/
9 Sidossis, L, et al; “Glucose and insulin-induced inhibition of fatty acid oxidation: the glucose-fatty acid cycle reversed”; American Journal of Physiology; 270(4 Pt 1):E733-8; April 1996; https://pubmed.ncbi.nlm.nih.gov/8928782
10 Bonadonna, R; “Dose-dependent effect of insulin on plasma free fatty acid turnover and oxidation in humans”; The American Journal of Physiology; 259(5 Pt 1):E736-50; November 1990; https://pubmed.ncbi.nlm.nih.gov/2240211
11 Rosell, Meritxell et al; “Brown and white adipose tissues: intrinsic differences in gene expression and response to cold exposure in mice.”; American journal of physiology. Endocrinology and metabolism; vol. 306,8; 2014; E945-64; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989735/
12 Saito, Masayuki; “Human Brown Adipose Tissue: Regulation and Anti-Obesity Potential.”; Endocrine Journal; U.S. National Library of Medicine; 2014; https://pubmed.ncbi.nlm.nih.gov/24401694
13 Iwami, Momoe, et al; “Extract of Grains of Paradise and Its Active Principle 6-Paradol Trigger Thermogenesis of Brown Adipose Tissue in Rats.”; Autonomic Neuroscience : Basic & Clinical; U.S. National Library of Medicine; 26 Apr. 2011; https://pubmed.ncbi.nlm.nih.gov/21185236
14 Sugita, Jun, et al; “Daily Ingestion of Grains of Paradise (Aframomum Melegueta) Extract Increases Whole-Body Energy Expenditure and Decreases Visceral Fat in Humans.”; Journal of Nutritional Science and Vitaminology; U.S. National Library of Medicine; 2014; https://www.jstage.jst.go.jp/article/jnsv/60/1/60_22/_pdf
15 Gaire, Bhakta Prasad et al; “Neuroprotective effect of 6-paradol in focal cerebral ischemia involves the attenuation of neuroinflammatory responses in activated microglia.”; PloS one; vol. 10,3; e0120203; 19 Mar. 2015; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366308/
16 Adefegha, Stephen A. et al; “Alligator pepper/Grain of Paradise (Aframomum melegueta) modulates Angiotensin-I converting enzyme activity, lipid profile and oxidative imbalances in a rat model of hypercholesterolemia”; Pathophysiology; Volume 23, Issue 3, 191 – 202; https://www.pathophysiologyjournal.com/article/S0928-4680(16)30026-8/fulltext
Metabolic Accelerator PM Supplement Facts
How To Use
Metabolic Accelerator PM Usage
For best results, take two (2) capsules prior to bedtime or as suggested by a qualified healthcare professional.
How To Stack
How To Stack Metabolic Accelerator PM
Use only as directed. Consult Your health care provider before use if you are pregnant or nursing, have a serious medical condition, or use prescription medications. For adult use only. Do not use in conjunction with alcoholic beverages, when driving a vehicle or while operating machinery. DO NOT USE IF SAFETY SEAL IS MISSING. Keep out of reach of children.